基因集做生存分析的在线工具

GenomicScape

传送门：http://genomicscape.com/microarray/survival.php

表面上看是可以基于给定的 gene list 做生存分析，但实际上出的图只是输入基因 + 自动搜索匹配出的相关基因各自分别作图得出的好多页的pdf…

KM-Express

Chen X, Miao Z, Divate M, et al. KM-express: an integrated online patient survival and gene expression analysis tool for the identification and functional characterization of prognostic markers in breast and prostate cancers[J]. Database, 2018, 2018.

传送门：http://ec2-52-201-246-161.compute-1.amazonaws.com/kmexpress/index.php

随便输进去几个基因，似乎是可行的…？

UALCAN

基于PERL

Chandrashekar D S, Bashel B, Balasubramanya S A H, et al. UALCAN: a portal for facilitating tumor subgroup gene expression and survival analyses[J]. Neoplasia, 2017, 19(8): 649-658.

传送门：http://ualcan.path.uab.edu/

但似乎实际上还是基于单基因，多了一些其他参数

Kaplan–Meier plots showing the association of EZH2 expression and other clinical parameters with patient survival. (A) KM plot depicting association of EZH2 expression levels with patient survival. (B) KM plot depicting association of EZH2 expression levels and race with patient survival. (C) KM plot depicting association of EZH2 expression level and BRCA subtype with patient survival. (D) KM plot depicting association of EZH2 expression levels and menopause status with patient survival.

Path2Surv

基于R

是一个算法：https://github.com/mehmetgonen/path2surv

Dereli O, Oğuz C, Gönen M. Path2Surv: Pathway/gene set-based survival analysis using multiple kernel learning[J]. Bioinformatics, 2019.

文章里主要是Path2Surv和其他算法的对比，没有看到成图。

CASAS

整合了多种生存分析的 shiny 工具。

Kowalski-Muegge J, Rupji M, Zhang X. CASAS: Cancer Survival Analysis Suite, a web based application[J]. F1000Research, 2017, 6: 919.

传送门：http://shinygispa.winship.emory.edu/CASAS/.

GitHub: https://github.com/manalirupji/CASAS/

眼拙没看出什么亮点，似乎不是搜索目标…不过可以作为 shiny 搭建参考。

SevenBridges Platform

一个简称是SB的公司的商业平台，要用需要先留邮箱 contact them，看来是没有免费/试用的端口。

传送门：https://www.sevenbridges.com/case-studies/e-nios/