• 以rb模式读取文件
• 文件较大时可分块读取 ```python

  !/usr/bin/env python

  -- encoding: utf8 --

  import hashlib

def md5sum(filename, size=4096):

md5 = hashlib.md5()
with open(filename, 'rb') as f:
    while True:
        b = f.read(size)
        if not b:
            break
        md5.update(b)
return md5.hexdigest()

if name == ‘main‘:

import sys
if len(sys.argv) < 2:
    print 'usage: %s <infile>' % sys.argv[0]
    exit()
infile = sys.argv[1]
md5_value = md5sum(infile)
print '{}  {}'.format(md5_value, infile)

``` 运行结果